SATB2 Back

SATB homeobox 2

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NCBI Description of SATB2
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.

Community Annotation of SATB2 Add / Edit SATB2: Annotations

No community annotations yet for SATB2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SATB2 is highly significantly mutated in
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SATB2 is significantly mutated in
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SATB2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SATB2