S1PR3 Back

sphingosine-1-phosphate receptor 3

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NCBI Description of S1PR3

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


S1PR3 is highly significantly mutated in
S1PR3 is significantly mutated in
S1PR3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for S1PR3