RXFP1 Back

relaxin/insulin-like family peptide receptor 1

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NCBI Description of RXFP1
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of RXFP1 Add / Edit RXFP1: Annotations

No community annotations yet for RXFP1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RXFP1 is highly significantly mutated in
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RXFP1 is significantly mutated in
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RXFP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RXFP1