External References:
Wikipedia
GeneCards
HUGO
COSMIC
Google Scholar
NCBI Description of RUFY1 |
This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Community Annotation of RUFY1 Add / Edit RUFY1: Annotations
No community annotations yet for RUFY1.
|
Figure notes
• "Mouse over" a mutation to see details. |
|
Click on a tumor type to see its full list of significant genes.
Data details