RTN2 Back

reticulon 2

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NCBI Description of RTN2
This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12.

Community Annotation of RTN2 Add / Edit RTN2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RTN2 is highly significantly mutated in
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RTN2 is significantly mutated in
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RTN2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RTN2