RTN1 Back

reticulon 1

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NCBI Description of RTN1

This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants.

Community Annotation of RTN1 Add / Edit RTN1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RTN1 is highly significantly mutated in
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RTN1 is significantly mutated in
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RTN1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RTN1