RPL28 Back

ribosomal protein L28

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of RPL28
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Community Annotation of RPL28 Add / Edit RPL28: Annotations

No community annotations yet for RPL28.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RPL28 is highly significantly mutated in
(none)
RPL28 is significantly mutated in
(none)
RPL28 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RPL28