RNF43 Back

ring finger protein 43

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NCBI Description of RNF43

RNF43 is a HAP95 (AKAP8L; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824]; Sugiura et al., 2008 [PubMed 18313049]).[supplied by OMIM, Dec 2008].

Community Annotation of RNF43 Add / Edit RNF43: Annotations

No community annotations yet for RNF43.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


RNF43 is highly significantly mutated in
RNF43 is significantly mutated in
RNF43 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for RNF43