RNF41 Back

ring finger protein 41

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NCBI Description of RNF41
This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.

Community Annotation of RNF41 Add / Edit RNF41: Annotations

No community annotations yet for RNF41.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RNF41 is highly significantly mutated in
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RNF41 is significantly mutated in
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RNF41 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RNF41