RNF25 Back

ring finger protein 25

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NCBI Description of RNF25
The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination.

Community Annotation of RNF25 Add / Edit RNF25: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RNF25 is highly significantly mutated in
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RNF25 is significantly mutated in
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RNF25 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RNF25