RNF181 Back

ring finger protein 181

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NCBI Description of RNF181

RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).[supplied by OMIM, Dec 2008].

Community Annotation of RNF181 Add / Edit RNF181: Annotations

No community annotations yet for RNF181.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


RNF181 is highly significantly mutated in
RNF181 is significantly mutated in
RNF181 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for RNF181