RNF141 Back

ring finger protein 141

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NCBI Description of RNF141
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients. Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RNF141 is highly significantly mutated in
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RNF141 is significantly mutated in
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RNF141 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RNF141