RNF11 Back

ring finger protein 11

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NCBI Description of RNF11

The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B). The germline mutations in RET gene are known to be responsible for the development of multiple endocrine neoplasia (MEN).

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RNF11 is highly significantly mutated in
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RNF11 is significantly mutated in
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RNF11 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RNF11