RND3 Back

Rho family GTPase 3

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NCBI Description of RND3

This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RND3 is highly significantly mutated in
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RND3 is significantly mutated in
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RND3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RND3