RNASEL Back

ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)

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NCBI Description of RNASEL
This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.

Community Annotation of RNASEL Add / Edit RNASEL: Annotations

No community annotations yet for RNASEL.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RNASEL is highly significantly mutated in
(none)
RNASEL is significantly mutated in
(none)
RNASEL is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RNASEL