RLIM Back

ring finger protein, LIM domain interacting

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NCBI Description of RLIM
The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Community Annotation of RLIM Add / Edit RLIM: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RLIM is highly significantly mutated in
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RLIM is significantly mutated in
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RLIM is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RLIM