RILP Back

Rab interacting lysosomal protein

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of RILP

This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology.

Community Annotation of RILP Add / Edit RILP: Annotations

No community annotations yet for RILP.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RILP is highly significantly mutated in
(none)
RILP is significantly mutated in
(none)
RILP is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RILP