RPTOR independent companion of MTOR, complex 2

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NCBI Description of RICTOR

RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008].

Community Annotation of RICTOR Add / Edit RICTOR: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


RICTOR is highly significantly mutated in
RICTOR is significantly mutated in
RICTOR is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for RICTOR