RIC3 Back

resistance to inhibitors of cholinesterase 3 homolog (C. elegans)

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NCBI Description of RIC3
The protein encoded by this gene promotes functional expression of homomeric nicotinic acetylcholine receptors at the cell surface. It enhances currents generated by these receptors by expediting receptor transport to the cell surface and by increasing receptor number. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of RIC3 Add / Edit RIC3: Annotations

No community annotations yet for RIC3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RIC3 is highly significantly mutated in
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RIC3 is significantly mutated in
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RIC3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RIC3