RHOBTB2 Back

Rho-related BTB domain containing 2

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NCBI Description of RHOBTB2
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of RHOBTB2 Add / Edit RHOBTB2: Annotations

No community annotations yet for RHOBTB2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RHOBTB2 is highly significantly mutated in
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RHOBTB2 is significantly mutated in
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RHOBTB2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RHOBTB2