RHBDL2 Back

rhomboid, veinlet-like 2 (Drosophila)

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NCBI Description of RHBDL2
The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3.

Community Annotation of RHBDL2 Add / Edit RHBDL2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RHBDL2 is highly significantly mutated in
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RHBDL2 is significantly mutated in
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RHBDL2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RHBDL2