RGS19 Back

regulator of G-protein signaling 19

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NCBI Description of RGS19

G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Community Annotation of RGS19 Add / Edit RGS19: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RGS19 is highly significantly mutated in
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RGS19 is significantly mutated in
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RGS19 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RGS19