RGS12 Back

regulator of G-protein signaling 12

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NCBI Description of RGS12
This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined.

Community Annotation of RGS12 Add / Edit RGS12: Annotations

No community annotations yet for RGS12.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RGS12 is highly significantly mutated in
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RGS12 is significantly mutated in
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RGS12 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RGS12