REXO2 Back

REX2, RNA exonuclease 2 homolog (S. cerevisiae)

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NCBI Description of REXO2

This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

REXO2 is highly significantly mutated in
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REXO2 is significantly mutated in
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REXO2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for REXO2