REG3A Back

regenerating islet-derived 3 alpha

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NCBI Description of REG3A

This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Alternate splicing results in multiple transcript variants that encode the same protein.

Community Annotation of REG3A Add / Edit REG3A: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


REG3A is highly significantly mutated in
REG3A is significantly mutated in
REG3A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for REG3A