RECQL Back

RecQ protein-like (DNA helicase Q1-like)

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NCBI Description of RECQL
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.

Community Annotation of RECQL Add / Edit RECQL: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RECQL is highly significantly mutated in
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RECQL is significantly mutated in
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RECQL is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RECQL