RDH10 Back

retinol dehydrogenase 10 (all-trans)

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NCBI Description of RDH10

This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development.

Community Annotation of RDH10 Add / Edit RDH10: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


RDH10 is highly significantly mutated in
RDH10 is significantly mutated in
RDH10 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for RDH10