RCHY1 Back

ring finger and CHY zinc finger domain containing 1

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NCBI Description of RCHY1
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Community Annotation of RCHY1 Add / Edit RCHY1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RCHY1 is highly significantly mutated in
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RCHY1 is significantly mutated in
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RCHY1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RCHY1