RCBTB2 Back

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2

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NCBI Description of RCBTB2

This gene encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran.

Community Annotation of RCBTB2 Add / Edit RCBTB2: Annotations

No community annotations yet for RCBTB2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RCBTB2 is highly significantly mutated in
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RCBTB2 is significantly mutated in
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RCBTB2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RCBTB2