RBP4 Back

retinol binding protein 4, plasma

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of RBP4

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

Community Annotation of RBP4 Add / Edit RBP4: Annotations

No community annotations yet for RBP4.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


RBP4 is highly significantly mutated in
RBP4 is significantly mutated in
RBP4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for RBP4