RBM14 Back

RNA binding motif protein 14

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NCBI Description of RBM14
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.

Community Annotation of RBM14 Add / Edit RBM14: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RBM14 is highly significantly mutated in
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RBM14 is significantly mutated in
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RBM14 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RBM14