RBAK Back

RB-associated KRAB zinc finger

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of RBAK
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus.

Community Annotation of RBAK Add / Edit RBAK: Annotations

No community annotations yet for RBAK.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RBAK is highly significantly mutated in
(none)
RBAK is significantly mutated in
(none)
RBAK is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RBAK