NCBI Description of RASSF8
|This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.|
Community Annotation of RASSF8 Add / Edit RASSF8: Annotations
No community annotations yet for RASSF8.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.