RASSF6 Back

Ras association (RalGDS/AF-6) domain family member 6

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of RASSF6
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms.

Community Annotation of RASSF6 Add / Edit RASSF6: Annotations

No community annotations yet for RASSF6.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RASSF6 is highly significantly mutated in
(none)
RASSF6 is significantly mutated in
(none)
RASSF6 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RASSF6