RAS protein activator like 2

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NCBI Description of RASAL2

This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Community Annotation of RASAL2 Add / Edit RASAL2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


RASAL2 is highly significantly mutated in
RASAL2 is significantly mutated in
RASAL2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for RASAL2