retinoic acid receptor responder (tazarotene induced) 2

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NCBI Description of RARRES2

This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


RARRES2 is highly significantly mutated in
RARRES2 is significantly mutated in
RARRES2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for RARRES2