RARRES1 Back

retinoic acid receptor responder (tazarotene induced) 1

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NCBI Description of RARRES1
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RARRES1 is highly significantly mutated in
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RARRES1 is significantly mutated in
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RARRES1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RARRES1