RAP2B Back

RAP2B, member of RAS oncogene family

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of RAP2B
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.

Community Annotation of RAP2B Add / Edit RAP2B: Annotations

No community annotations yet for RAP2B.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAP2B is highly significantly mutated in
(none)
RAP2B is significantly mutated in
(none)
RAP2B is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RAP2B