RAGE Back

renal tumor antigen

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NCBI Description of RAGE
This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Community Annotation of RAGE Add / Edit RAGE: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAGE is highly significantly mutated in
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RAGE is significantly mutated in
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RAGE is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RAGE