NCBI Description of RAD54L
|The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.|
Community Annotation of RAD54L Add / Edit RAD54L: Annotations
No community annotations yet for RAD54L.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.