RAD52 Back

RAD52 homolog (S. cerevisiae)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of RAD52

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.

Community Annotation of RAD52 Add / Edit RAD52: Annotations

No community annotations yet for RAD52.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAD52 is highly significantly mutated in
(none)
RAD52 is significantly mutated in
(none)
RAD52 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RAD52