RAB8B Back

RAB8B, member RAS oncogene family

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NCBI Description of RAB8B
RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010].

Community Annotation of RAB8B Add / Edit RAB8B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAB8B is highly significantly mutated in
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RAB8B is significantly mutated in
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RAB8B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RAB8B