RAB4A Back

RAB4A, member RAS oncogene family

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NCBI Description of RAB4A
This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene.

Community Annotation of RAB4A Add / Edit RAB4A: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAB4A is highly significantly mutated in
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RAB4A is significantly mutated in
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RAB4A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RAB4A