RAB2A Back

RAB2A, member RAS oncogene family

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NCBI Description of RAB2A
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of RAB2A Add / Edit RAB2A: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAB2A is highly significantly mutated in
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RAB2A is significantly mutated in
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RAB2A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RAB2A