RAB27A Back

RAB27A, member RAS oncogene family

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NCBI Description of RAB27A

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAB27A is highly significantly mutated in
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RAB27A is significantly mutated in
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RAB27A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RAB27A