RAB25 Back

RAB25, member RAS oncogene family

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NCBI Description of RAB25

RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007 [PubMed 17925226]).[supplied by OMIM, Aug 2009].

Community Annotation of RAB25 Add / Edit RAB25: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAB25 is highly significantly mutated in
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RAB25 is significantly mutated in
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RAB25 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RAB25