RAB1A Back

RAB1A, member RAS oncogene family

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NCBI Description of RAB1A

This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms.

Community Annotation of RAB1A Add / Edit RAB1A: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


RAB1A is highly significantly mutated in
RAB1A is significantly mutated in
RAB1A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for RAB1A