RAB18 Back

RAB18, member RAS oncogene family

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NCBI Description of RAB18
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of RAB18 Add / Edit RAB18: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAB18 is highly significantly mutated in
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RAB18 is significantly mutated in
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RAB18 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RAB18