RAB14 Back

RAB14, member RAS oncogene family

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NCBI Description of RAB14
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009].

Community Annotation of RAB14 Add / Edit RAB14: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAB14 is highly significantly mutated in
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RAB14 is significantly mutated in
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RAB14 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for RAB14