RAB11B Back

RAB11B, member RAS oncogene family

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NCBI Description of RAB11B

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010].

Community Annotation of RAB11B Add / Edit RAB11B: Annotations

No community annotations yet for RAB11B.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

RAB11B is highly significantly mutated in
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RAB11B is significantly mutated in
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RAB11B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for RAB11B